From: CIRBP mRNA level in breast cancer is associated with HIF1α gene expression and microvascular density
Variables | CIRBP | HIF1α | ||
---|---|---|---|---|
Mean fold change(± SD) | p-value | Mean fold change(± SD) | p-value | |
Tumor size (cm) | ||||
< 5 ≥ 5 | 4.213(± 0.295) 5.646 (± 0.485) | 0.016* | 4.027(± 0.229) 4.855 (± 0.223) | 0.015* |
Grade | ||||
I II III | 3.659(± 0.450) 4.276(± 0.362) 6.585(± 0.495) | <0.001* | 3.871(± 0.337) 4.290(± 0.222) 5.075(0.296) | 0.027* |
Stage | ||||
II III | 4.534(± 0.322) 6.158(± 0.660) | 0.018* | 4.174(± 0.183) 5.317(± 0.276) | 0.002* |
ER | ||||
Positive Negative | 5.429(± 0.407) 4.364(± 0.467) | 0.097 | 4.611(± 0.231) 4.337(± 0255) | 0.660 |
PR | ||||
Positive Negative | 5.464(± 0.432) 4.434(± 0.435) | 0.104 | 4.698(± 0.216) 4.693(± 0.214) | 0.208 |
P53 | ||||
Positive Negative | 4.420(± 0.573) 5.354(± 0.357) | 0.152 | 4.187(0.275) 4.693(± 0.214) | 0.154 |
Necrosis | ||||
Yes No | 5.406(± 0.437) 4.264(± 0.334) | 0.045* | 4.692(± 0.225) 4.154(± 0.240) | 0.135 |
Lymphatic invasion | ||||
Yes No | 5.639(± 0.412) 3.956(± 0.365) | 0.008* | 4.830(± 0.223) 3.964(0.211) | 0.012* |
Vascular invasion | ||||
Yes No | 5.639(± 0.412) 3.956(± 0.365) | 0.008* | 4.830(± 0.223) 3.964(0.211) | 0.012* |