Fig. 2

A Hallmark (H) pathways significantly downregulated by IL-13 treatment (IL13) compared to control (CTR). The size of the dot represents the Normalized Enrichment Score (NES), indicating the strength of pathway enrichment in a given cell type, with larger dots reflecting stronger enrichment. The color of the dot represents p-adjusted value, indicating the statistical significance of the pathway. B Pathways significantly downregulated in Tollip knockout + IL-13-treated (TKDIL13) compared to Tollip knockout-only (TKD)