Table 1 Cancer gene census (CGC) variants in all COSMIC variants from DSMZ breast cancer cell lines
Cell line | Gene symbol | HGVSG | Mutation AA | Mutation description |
|---|---|---|---|---|
BT-474 | PIK3CA | 3:g.179199158G C | p.K111N | Substitution - Missense |
CAL-148 | PTEN | 10:g.87957976T A | p.I253N | Substitution - Missense |
CAL-148 | PTEN | 10:g.87960984C T | p.Q298 | Substitution - Nonsense |
CAL-148 | PIK3CA | 3:g.179234297A G | p.H1047R | Substitution - Missense |
CAL-51 | PIK3CA | 3:g.179218294G A | p.E542K | Substitution - Missense |
DU-4475 | APC | 5:g.112840323G T | p.E1577 | Substitution - Nonsense |
EFM-19 | PIK3CA | 3:g.179234297A T | p.H1047L | Substitution - Missense |
EVSA-T | PTEN | 10:g.87961047_87961050del | p.T319 | Deletion - Frameshift |
EVSA-T | TP53 | 17:g.7674241G C | p.S241C | Substitution - Missense |
MFM-223 | PIK3CA | 3:g.179234297A G | p.H1047R | Substitution - Missense |