Fig. 1

Morphological and phonotypical characterization of BM-MSCs utilized to obtain MSC-CM. A-C are representative micrographs of the BM-MSCs at day 4, day 12, and 4th passage cells. Adherent cells exhibited a typical fibroblast-like spindle shape. “1D” through “1H” represent the expression of the clusters of differentiation (CD), including positive markers (CD105&CD90) and three hematopoietic markers (CD45, CD34, and CD19). The bar graph “1I” depicts the mean (± SD) of the relative expression of 3 independent flow cytometry analyses for each marker