Fig. 1
Chemical structures of DIF compounds. A DIF-1 (1), 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one. DIF-3 (2), 1-(3-chloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one. Ph-DIF-1 (3), 1-(3,5-dichloro-2,6-dihydroxy-4-phenoxyphenyl)hexan-1-one. Bu-DIF-3 (4), 1-(3-chloro-2,6-dihydroxy-4-butoxyphenyl)hexan-1-one. DIF-1-NH2 (5), 6-amino-1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one. NH2-Bu-DIF-3 (6), 1-(4-(4-aminobutoxy)-3-chloro-2,6-dihydroxyphenyl)hexan-1-one. Note that 6 is a synthetic intermediate of BODIPY-DIF-3G [25]. B Ester derivatives of 3 and 4. Ph-DIF-1(AHA) (7), Ph-DIF-1–aminohexanoic acid ester, 2,4-dichloro-6-hexanoyl-5-hydroxy-3-phenoxyphenyl 6-aminohexanoate. Bu-DIF-3(2Ac) (8), Bu-DIF-3–acetic acid ester, 5-butoxy-4-chloro-2-hexanoyl-1,3-phenylene diacetate