Table 1 Baseline characteristics of the patients according to haemoglobin levels he patients according to haemoglobin levels
From: Severe anaemia in people with HIV: demographic, clinical and renal correlates
Variable | Total | Anaemia Status | P-value | ||
|---|---|---|---|---|---|
No Anaemia | Mild-Mod | Severe | |||
Age Mean SD | 372 | 44.7 ± 12.1 | 45.4 ± 12.5 | 43.7 ± 13.9 | 0.464 |
Sex | < 0.001 | ||||
Male | 136 | 104 (76.5) | 27 (19.9) | 5 (3.7) | |
Female | 234 | 72 (30.8) | 132 (56.4) | 30 (12.8) | |
Total | 370 | 176 | 159 | 35 | |
Regimen | n = 369 | 0.016 | |||
PI | 46 | 25 (54.3) | 18 (39.1) | 4 (8.7) | |
INSTI | 65 | 43 (66.2) | 20 (30.8) | 2 (3.1) | |
NNRTI | 258 | 108 (40.3) | 121 (47.5) | 29 (11.2) | |
Total | 369 | 176 | 159 | 35 | |
Physical exercise | 0.035 | ||||
Yes | 105 | 61 (58.1) | 38 (36.2) | 6 (5.7) | |
No | 261 | 114 (41.1) | 120 (46.7) | 27 (10.3) | |
Total | 366 | 175 | 158 | 33 | |
Alcohol n = 366 | 0.002 | ||||
Yes | 210 | 117 (55.7) | 76 (36.2) | 17 (8.1) | |
No | 159 | 59 (37.1) | 82 (51.6) | 18 (11.3) | |
total | 369 | 176 | 158 | 35 | |
Renal Insufficiency | n = 367 | < 0.001 | |||
Normal | 164 | 64 (39) | 78 (47.6) | 22 (13.4) | |
Mild | 174 | 98 (56.3) | 70 (40.2) | 6 (3.4) | |
Moderate | 27 | 12 (44.4) | 15 (55.6) | 0 (0) | |
Severe | 2 | 0 (0) | 1 (50) | 1 (50) | |
Total | 367 | 174 | 164 | 29 | |
Alt U/L | 361 | 15 (13, 27) | 19.7 (16, 26) | 16.9 (12, 26) | 0.16 |
Albumin g/dl | 288 | 42.4 (39, 46) | 41.9 (37, 44) | 40.7 (34, 43) | 0.009 |
Ast U/L | 365 | 31.1 (26, 40) | 30.4 (24, 43) | 30.8 (23, 40) | 0.92 |
CD4 + t (cells/mL) m(IQR) | 371 | 611 (394, 806) | 665 (363, 906) | 453 (325, 805) | 0.009 |
Creatinine mg/dL | 369 | 81.6 (70, 97) | 76.8 (67, 90) | 70.1 (66, 80) | 0.002 |
Duration ART mo, m(IQR) | 372 | 61 (8.5, 65.5) | 66.5(31, 71) | 64 (30.5, 73) | 0.02 |
VL(copies/mL) | 372 | 0 (0, 20190) | 0 (0, 84) | 20 (0, 91) | 0.92 |
BMI kg/m2, m(IQR) | 372 | 21.7 (18, 28) | 22.1 (19, 24) | 22.6 (20, 27) | 0.77 |
MAP mmHg | 372 | 87.2 (80, 99) | 82.8 (79, 89) | 84.3 (77, 92) | < 0.001 |
Weight m, IQR | 372 | 55 (49, 70) | 58.5 (52, 64) | 63 (52, 69) | 0.014 |
eGFR ml/min | 369 | 80 (62, 92) | 90 (80, 103) | 99 (90, 116) | 0.008 |
MCV fl. | 371 | 98 (92.5, 103) | 95.7(89, 101) | 91 (71.8, 96.5) | 0.051 |