Fig. 2

Receiver operating characteristic (ROC) curves for diagnostic markers. (a) Genomic content (Lane %) and β-globin gene expression versus IFNγ polymorphisms. (b) Genomic content (Lane %) and β-globin gene expression versus IL6 polymorphisms. (c) Genomic content (Lane %) and CRP (mg/dl) versus IFN γ polymorphisms. (d) Genomic content (Lane %) and CRP (mg/dl) versus IL6 polymorphisms. The gray-yellow line indicates the reference line (AUC = 0.5). The green line indicates the semi-quantified allele genomic content (Lane %). The blue line indicates the CRP (mg/dl). Axes Labels: X-axis: Specificity(False Positive Rate). Y-axis: Sensitivity(True Positive Rate). Each curve demonstrates diagnostic performance in distinguishing inflammatory and genetic profiles of Sudanese children with ESKD