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Table 4 Strongest (p < 0.2) associations between predictor variables and the saliva-based Inflammation and Physiological Dysregulation Index (IPDI), multiplicative effects with 95% confidence limits

From: Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers

Predictor variable

Number of observations

Fold change in IPDI*

P value

Allergy to house dust

20

2.11 (1.00; 4.41)

0.05

Allergy to house dust requiring treatment

20

2.07 (1.00; 4.28)

0.05

Age (per 10-year increase)

20

1.23 (0.99; 1.54)

0.06

Allergy to pollen requiring treatment

20

1.91 (0.92; 3.95)

0.08

DASS-21 stress score, per unit increase

17

1.11 (0.99; 1.25)

0.08

Self-reported chronic obesity

20

1.81 (0.92; 3.56)

0.08

Diabetes

20

1.67 (0.83; 3.34)

0.15

DASS-21 anxiety score, per unit increase

16

1.09 (0.97; 1.22)

0.15

Loss of employment during past year

19

1.65 (0.83; 3.29)

0.16

BMI, kg/m2 (per unit increase)

18

1.04 (0.98; 1.10)

0.16

Obesity (BMI ≥ 30 kg/m2)

18

1.70 (0.81; 3.56)

0.16

DASS-21 depression score, per unit increase

16

1.06 (0.98; 1.14)

0.17

  1. *Effect estimate for age is from a univariate model; all other effect estimates are adjusted for age