Table 6 Haplotype analysis of Interleukin 33, 22, 17, 13 and 4 genes between infertile patients and healthy controls
IL 33 haplotypes | Control/Patient freq | p | OR (95% CI) | IL 22 haplotypes | Control/Patient freq | p | OR (95% CI) |
|---|---|---|---|---|---|---|---|
GATC | – | – | Ref. | CATT | – | – | Ref. |
GACC | 11/ 7 | 0.02 | 0.6 (0.2–1.6) | CTTT | 87/68 | 0.05 | 1.4 (0.9–2.2) |
AATC | 19/17 | 0.08 | 0.9 (0.4–1.7) | TTAT | 18/11 | 0.01 | 1.6 (0.7–3.6) |
IL 17 haplotypes | Control/Patient freq | p | OR (95% CI) | IL 13 haplotypes | Control/Patient freq | p | OR (95% CI) |
|---|---|---|---|---|---|---|---|
GATC | – | – | Ref. | AACG | – | – | Ref. |
GACC | 20/12 | 0.1 | 1.7 (0.8–3.7) | ACGG | 9/4 | 0.00 | 3 (1.9–4.7) |
AATC | 17/6 | 0.1 | 3 (1.8–7.9) | GACC | 13/13 | 0.1 | 1 (0.4–2) |
IL 4 haplotypes | Control /Patient freq | p | OR (95% CI) | ||||
|---|---|---|---|---|---|---|---|
CCTT | – | – | Ref. | ||||
CTTT | 13/6 | 0.04 | 2.2 (0.8–6.1) | ||||
CTTC | 26/13 | 0.02 | 2.1 (1–4.3) |