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Table 2 CTLA-4 expression in advanced-stage CHL and its relationship with IPS

From: Cytotoxic T-lymphocyte-associated 4 protein expression is associated with a high international prognostic score in advanced-stage classical Hodgkin lymphoma

Variable

CTLA-4 expression

(mean ± SD)

p value

Age

  

 ≤ 45 years old

258.59 ± 98.49

0.757

 > 45 years old

243.64 ± 115.25

 

Sex

  

 Female

271.2 ± 107.67

0.387

 Male

243.62 ± 91.56

 

Haemoglobin

  

 < 10.5 g/dl

285.85 ± 115.31

0.077

 ≥ 10.5 g/dl

230.36 ± 75.46

 

Leukocyte

  

 ≤ 15,000 µ/L

219.11 ± 74.31

0.004

 > 15,000 µ/L

307.6 ± 107.79

 

Lymphocyte

  

 < 8%

279.62 ± 122.07

0.107

 ≥ 8%

228.74 ± 51.68

 

Albumin

  

 < 4 g/dl

261.06 ± 103.57

0.414

 ≥ 4 g/dl

217.65 ± 24.07

 

Stage

  

 < 4

210.23 ± 84.94

0.020

 4

284.62 ± 98.12

 

IPS

  

 Low IPS

210.11 ± 52.41

0.003

 High IPS

303.33 ± 113.52

 
  1. Unpaired T test; CTLA-4: cytotoxic T-lymphocyte-associated protein 4; SD: standard deviation