Table 2 Association of clinicopathological and prognostic parameters of colorectal carcinoma with T stage
Variable | T stage | P value | |||
|---|---|---|---|---|---|
T 1 | T2 | T3 | T4 | ||
Age (years) | |||||
< 50 | 0 | 2 | 31 | 4 | 0.84 |
> 50 | 1 | 5 | 50 | 7 | |
Gender | |||||
Male | 0 | 2 | 46 | 3 | 0.111 |
Female | 1 | 5 | 35 | 8 | |
Laterality | |||||
Right | 0 | 2 | 23 | 5 | 0.62 |
Left | 1 | 5 | 58 | 6 | |
Lymphovascular invasion | |||||
Present | 0 | 0 | 24 | 3 | 0.356 |
Absent | 1 | 7 | 57 | 8 | |
Grade | |||||
Well differentiated | 0 | 2 | 1 | 0 | < 0.001* |
Moderately differentiated | 1 | 5 | 65 | 5 | |
Poorly differentiated | 0 | 0 | 15 | 6 | |
Tumor type | |||||
Adenocarcinoma, NOS | 1 | 7 | 64 | 8 | 0.65 |
Mucinous carcinoma | 0 | 0 | 12 | 1 | |
Medullary carcinoma | 0 | 0 | 2 | 0 | |
Signet ring cell carcinoma | 0 | 0 | 3 | 2 | |
Perinodal spread | |||||
Present | 0 | 0 | 40 | 7 | 0.037* |
Absent | 1 | 7 | 41 | 4 | |
Mucinous histology (%) | |||||
Absent | 1 | 6 | 54 | 7 | 0.778 |
< 10 | 0 | 0 | 9 | 3 | |
10–50 | 0 | 0 | 7 | 0 | |
> 50 | 0 | 1 | 11 | 1 | |
Signet ring differentiation | |||||
Present | 0 | 1 | 13 | 2 | 0.97 |
Absent | 1 | 6 | 68 | 9 | |
Medullary differentiation | |||||
Present | 0 | 0 | 1 | 0 | 0.971 |
Absent | 1 | 7 | 80 | 11 | |
Necrosis | |||||
Absent | 0 | 0 | 4 | 2 | 0.228 |
Focal | 0 | 6 | 56 | 1 | |
Widespread | 1 | 1 | 21 | 8 | |
Tumor infiltrating lymphocytes | |||||
None | 0 | 3 | 50 | 5 | 0.047* |
Mild-moderate | 1 | 0 | 19 | 4 | |
Marked | 0 | 4 | 12 | 2 | |
Peri-tumoral lymphocytes | |||||
None | 0 | 7 | 53 | 7 | 0.166 |
Mild-moderate | 1 | 0 | 14 | 3 | |
Marked | 0 | 0 | 14 | 1 | |
Pre-existing polyp | |||||
Present | 1 | 2 | 7 | 0 | 0.004* |
Absent | 0 | 5 | 74 | 11 | |